Dimethylformamide → 4-Bromo-5-chlorothiophene-2-carbaldehyde
Reaction equation
[Br:13][c:14]1[c:15]([Cl:19])[s:16][cH:17][cH:18]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[O:20]=[CH:21][N:22]([CH3:23])[CH3:24]>>[Br:13][c:14]1[c:15]([Cl:19])[s:16][c:17]([CH:21]=[O:20])[cH:18]1Participants
6
Sources & evidence
- ORD record
- ord-b1d0e5fb493c47cfae1ada2f000238b6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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