Bromide ion → 4-But-3-en-1-yl-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine

HRID 956130Notes

Reaction equation

HRID 956130 reaction equation
[Br-:1].[Br-:24].[CH2:2]([CH2:3][CH:4]=[CH2:5])[Mg+:6].[Cl:7][c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[s:14][cH:15][c:16]2-[c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1.[Cu:30][I:31].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[CH2:2]([CH2:3][CH:4]=[CH2:5])[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[s:14][cH:15][c:16]2-[c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 259Bromide ion2×HCID 8028TetrahydrofuranHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 27829114-Chloro-5-(4-fluorophenyl)thieno(2,3-d)pyrimidineHCID 178448188HCID 178448188, compound

Product 1

HCID 116233584-But-3-en-1-yl-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-40c072d353e7451dab922ccab212bb3f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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