Water → N-(5'-(3-Fluoropropoxy)-4-methoxyspiro[cyclohexane-1,2'-indene]-3'(1'H)-yhdene)-2-methylpropane-2-sulfinamide

HRID 956205Notes

Reaction equation

HRID 956205 reaction equation
[CH3:23][C:24]([CH3:25])([CH3:26])[S:27](=[O:28])[NH2:29].[CH3:31][CH:32]1[CH2:33][CH2:34][CH2:35][O:36]1.[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[CH3:43][CH2:44][O-:45].[CH3:47][CH2:48][O-:49].[CH3:50][CH2:51][O-:52].[CH3:53][CH2:54][O-:55].[F:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]2[c:20]([cH:21]1)[C:19](=[O:22])[C:11]1([CH2:10]2)[CH2:12][CH2:13][CH:14]([O:17][CH3:18])[CH2:15][CH2:16]1.[OH2:30].[Ti+4:46]>>[F:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]2[c:20]([cH:21]1)[C:19](=[N:29][S:27]([C:24]([CH3:23])([CH3:25])[CH3:26])=[O:28])[C:11]1([CH2:10]2)[CH2:12][CH2:13][CH:14]([O:17][CH3:18])[CH2:15][CH2:16]1

Participants

8

Reactant 7

HCID 962WaterHCID 73012-MethyltetrahydrofuranHCID 8857Ethyl AcetateHCID 114942Titanium cation (4+)HCID 1194401-Hydroxyethyl radical4×HCID 3382465Tert-ButanesulfinamideHCID 679794516'-(3-Fluoropropoxy)-4-methoxyspiro[cyclohexane-1,2'-inden]-1'(3'H)-one

Product 1

HCID 67979469N-(5'-(3-Fluoropropoxy)-4-methoxyspiro[cyclohexane-1,2'-indene]-3'(1'H)-yhdene)-2-methylpropane-2-sulfinamide

Sources & evidence

ORD record
ord-a0fea9eda87d4bf7bcabdbcca5ff0e6d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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