Hydrochloric Acid → 3-((tert-Butyldimethylsilanyl)oxy)azetidine

HRID 956470Notes

Reaction equation

HRID 956470 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[Cl:8].[CH2:15]([N:16]([CH:17]([CH3:18])[CH3:19])[CH:20]([CH3:21])[CH3:22])[CH3:23].[Cl:24][CH2:25][Cl:26].[ClH:9].[NH:10]1[CH2:11][CH:12]([OH:14])[CH2:13]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:14][CH:12]1[CH2:11][NH:10][CH2:13]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 28928tert-Butyldimethylsilyl chlorideHCID 81531DiisopropylethylamineHCID 15142903-Hydroxyazetidine

Product 1

HCID 574386563-((tert-Butyldimethylsilanyl)oxy)azetidine

Sources & evidence

ORD record
ord-e1d98b55897e47419594968e7e3c4819
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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