Tetrahydrofuran → HCID 59639622, compound

HRID 956540Notes

Reaction equation

HRID 956540 reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:31])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:27]([CH3:28])(=[O:29])=[O:30])[n:17][c:18]3-[c:19]2[c:20]([CH3:26])[cH:21][c:22]([F:25])[cH:23][cH:24]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[NH2:32][CH:33]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:31])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([NH:32][CH:33]2[CH2:34][CH2:35][O:36][CH2:37][CH2:38]2)[n:17][c:18]3-[c:19]2[c:20]([CH3:26])[cH:21][c:22]([F:25])[cH:23][cH:24]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 4192234-AminotetrahydropyranHCID 596395548-(2,6-difluoro-phenyl)-4-(4-fluoro-2-methyl-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one

Product 1

HCID 59639622HCID 59639622, compound

Sources & evidence

ORD record
ord-0dcbaa4213764fd1b47dd4f1a699b8a0
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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