Tetrahydrofuran → Methyl 3-(oxolan-2-yl)-2-[4-(trifluoromethyl)imidazol-1-yl]propanoate
Reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:10][Si:11]([CH3:12])([CH3:13])[N-:14][Si:15]([CH3:16])([CH3:17])[CH3:18].[F:1][C:2]([c:3]1[n:4][cH:5][nH:6][cH:7]1)([F:8])[F:9].[Li+:19].[O:20]1[CH:21]([CH2:25][CH:26]([C:27](=[O:28])[O:29][CH3:30])[O:31][S:32]([C:33]([F:34])([F:35])[F:36])(=[O:37])=[O:38])[CH2:22][CH2:23][CH2:24]1>>[F:1][C:2]([c:3]1[n:4][cH:5][n:6]([CH:26]([CH2:25][CH:21]2[O:20][CH2:24][CH2:23][CH2:22]2)[C:27](=[O:28])[O:29][CH3:30])[cH:7]1)([F:8])[F:9]Participants
6
Sources & evidence
- ORD record
- ord-c62eb49802404e34b342c27da8c92b0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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