Dimethylformamide → Tert-butyl 2-[[4-[4-[(4-methoxy-3,5-dimethyl-1-benzofuran-2-carbonyl)amino]phenyl]phenyl]sulfonylamino]-3-methylbutanoate

HRID 956820Notes

Reaction equation

HRID 956820 reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22]([CH:23]([CH:24]([CH3:25])[CH3:26])[NH:27][S:28](=[O:29])(=[O:30])[c:31]1[cH:32][cH:33][c:34](-[c:37]2[cH:38][cH:39][c:40]([NH2:43])[cH:41][cH:42]2)[cH:35][cH:36]1)=[O:44].[CH3:1][O:2][c:3]1[c:4]([CH3:16])[cH:5][cH:6][c:7]2[c:8]1[c:9]([CH3:15])[c:10]([C:12](=[O:13])[OH:14])[o:11]2.[CH:72]([N:73]([CH2:74][CH3:75])[CH:76]([CH3:77])[CH3:78])([CH3:79])[CH3:80].[O:81]=[CH:82][N:83]([CH3:84])[CH3:85].[P-:45]([F:46])([F:47])([F:48])([F:49])([F:50])[F:51].[n:52]1([O:53][P+:54]([N:55]([CH3:56])[CH3:57])([N:58]([CH3:59])[CH3:60])[N:61]([CH3:62])[CH3:63])[c:64]2[cH:65][cH:66][cH:67][cH:68][c:69]2[n:70][n:71]1>>[CH3:1][O:2][c:3]1[c:4]([CH3:16])[cH:5][cH:6][c:7]2[c:8]1[c:9]([CH3:15])[c:10]([C:12](=[O:14])[NH:43][c:40]1[cH:39][cH:38][c:37](-[c:34]3[cH:33][cH:32][c:31]([S:28]([NH:27][CH:23]([C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:44])[CH:24]([CH3:25])[CH3:26])(=[O:29])=[O:30])[cH:36][cH:35]3)[cH:42][cH:41]1)[o:11]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 124335Benzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 68711776Tert-butyl 2-[[4-(4-aminophenyl)phenyl]sulfonylamino]-3-methylbutanoateHCID 687142664-Methoxy-3,5-dimethyl-benzofuran-2-carboxylic acid

Product 1

HCID 68713926Tert-butyl 2-[[4-[4-[(4-methoxy-3,5-dimethyl-1-benzofuran-2-carbonyl)amino]phenyl]phenyl]sulfonylamino]-3-methylbutanoate

Sources & evidence

ORD record
ord-5e8fc723ff914c2daa2ee036bea37977
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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