Triethylamine → 2-(4-Fluorophenyl)-5-cyanopyridine

HRID 956982Notes

Reaction equation

[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:24][CH2:25][O:26][C:27](=[O:28])[CH3:29].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([Cl:16])[c:11]([C:14]#[N:15])[cH:12][cH:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([C:14]#[N:15])[cH:12][cH:13]2)[cH:6][cH:7]1

Participants

Reactant 3

HCID 8471Triethylamine

HCID 8857Ethyl Acetate

HCID 27737342-Chloro-6-(4-Fluorophenyl)Nicotinonitrile

Product 1

HCID 139315862-(4-Fluorophenyl)-5-cyanopyridine

Sources & evidence

ORD record: ord-0810ca13e33149ab8a2eede95a8d22dd
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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