Hydrochloric Acid → Ethyl 2-hydroxy-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionate

HRID 957034Notes

Reaction equation

HRID 957034 reaction equation
[C:1]([O:2][C:6](=[O:7])[NH:8][CH2:9][CH2:10][O:11][c:12]1[cH:13][cH:14][c:15]([CH2:18][CH:19]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[OH:25])[cH:16][cH:17]1)([CH3:3])([CH3:4])[CH3:5].[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[ClH:26].[n:27]1[c:28](-[c:33]2[cH:34][cH:35][c:36]([C:37]([Cl:38])=[O:39])[cH:40][cH:41]2)[cH:29][cH:30][cH:31][cH:32]1>>[C:6](=[O:7])([NH:8][CH2:9][CH2:10][O:11][c:12]1[cH:13][cH:14][c:15]([CH2:18][CH:19]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[OH:25])[cH:16][cH:17]1)[c:36]1[cH:35][cH:34][c:33](-[c:28]2[n:27][cH:32][cH:31][cH:30][cH:29]2)[cH:41][cH:40]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 8471TriethylamineHCID 120170524-(2-Pyridinyl)benzoyl ChlorideHCID 18625730Ethyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-hydroxypropionate

Product 1

HCID 18625968Ethyl 2-hydroxy-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionate

Sources & evidence

ORD record
ord-1164628e78bc48f6829cd99c9530f4a6
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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