Hydrogen Bromide → 4-(4-(Methylsulfonyl)piperazin-1-yl)phenol

HRID 957293Notes

Reaction equation

HRID 957293 reaction equation
[BrH:1].[BrH:2].[C:19](=[O:20])([O-:21])[OH:22].[CH3:16][CH2:17][OH:18].[CH3:24][S:25]([Cl:26])(=[O:27])=[O:28].[N:3]1([c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)[CH2:4][CH2:5][NH:6][CH2:7][CH2:8]1.[Na+:23].[OH2:29]>>[N:3]1([c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)[CH2:4][CH2:5][N:6]([S:25]([CH3:24])(=[O:27])=[O:28])[CH2:7][CH2:8]1

Participants

8

Reactant 7

HCID 260Hydrogen Bromide2×HCID 702EthanolHCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 31297Methanesulfonyl chlorideHCID 92467p-(1-Piperazinyl)phenol

Product 1

HCID 6400494-(4-(Methylsulfonyl)piperazin-1-yl)phenol

Sources & evidence

ORD record
ord-719caaf395354432b4821aca67f47466
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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