Tetrahydrofuran → Tert-butyl 2-[(2-azidobenzoyl)-formylamino]propanoate

HRID 957540Notes

Reaction equation

HRID 957540 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([CH3:8])[NH:9][CH:10]=[O:11])=[O:12].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:14][CH:15]([N-:16][CH:17]([CH3:18])[CH3:19])[CH3:20].[Li+:13].[N:21](=[N+:22]=[N-:23])[c:24]1[c:25]([C:26](=[O:27])[Cl:28])[cH:29][cH:30][cH:31][cH:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([CH3:8])[N:9]([CH:10]=[O:11])[C:26]([c:25]1[c:24]([N:21]=[N+:22]=[N-:23])[cH:32][cH:31][cH:30][cH:29]1)=[O:27])=[O:12]

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 117452552-Azidobenzoyl chlorideHCID 23498682Tert-butyl 2-formamidopropanoate

Product 1

HCID 90709055Tert-butyl 2-[(2-azidobenzoyl)-formylamino]propanoate

Sources & evidence

ORD record
ord-0ae3cdb3c26d4c98837f614ff61fd5f9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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