Hydrochloric Acid → N-Methyldesloratadine
Reaction equation
[CH3:2][N:3]1[CH2:4][CH2:5][CH:6]([C:9](=[O:10])[c:11]2[n:12][cH:13][cH:14][cH:15][c:16]2[CH2:17][CH2:18][c:19]2[cH:20][c:21]([Cl:25])[cH:22][cH:23][cH:24]2)[CH2:7][CH2:8]1.[ClH:1].[OH:26][S:27]([C:28]([F:29])([F:30])[F:31])(=[O:32])=[O:33]>>[CH3:2][N:3]1[CH2:4][CH2:5][C:6](=[C:9]2[c:11]3[n:12][cH:13][cH:14][cH:15][c:16]3[CH2:17][CH2:18][c:19]3[cH:20][c:21]([Cl:25])[cH:22][cH:23][c:24]32)[CH2:7][CH2:8]1Participants
4
Sources & evidence
- ORD record
- ord-3707214bd18d44db89116a6371b04906
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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