Acetonitrile → 5-Bromo-2-methyl-1-t-butyloxycarbonylindole

HRID 957795Notes

Reaction equation

HRID 957795 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([CH3:11])[nH:7][c:8]2[cH:9][cH:10]1.[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17]([O:18][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:19].[CH3:24][C:25]#[N:26].[CH3:27][N:28]([CH3:29])[c:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1.[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41]>>[Br:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([CH3:11])[n:7]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[c:8]2[cH:9][cH:10]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 142844-(Dimethylamino)pyridineHCID 50039685-Bromo-2-methylindoleHCID 10219638Carbonic acid, bis(1,1-dimethylethyl) ester

Product 1

HCID 218654515-Bromo-2-methyl-1-t-butyloxycarbonylindole

Sources & evidence

ORD record
ord-b3725ca386a447f3b5ddc1909715980b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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