Potassium Cation → 4-(2-Methoxy-ethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

HRID 958160Notes

Reaction equation

HRID 958160 reaction equation
[Br:19][CH2:20][CH2:21][O:22][CH3:23].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[K+:29].[N:1]1([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:2][CH2:3][CH:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[CH2:5][CH2:6]1.[S:24](=[O:25])(=[O:26])([OH:27])[O-:28]>>[N:1]1([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:2][CH2:3][C:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])([CH2:20][CH2:21][O:22][CH3:23])[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 61778Sulfate, hydrogenHCID 809722-Bromoethyl methyl etherHCID 27588121-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

Product 1

HCID 582872614-(2-Methoxy-ethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Sources & evidence

ORD record
ord-d9436451249d4061ac7ade209501fcc1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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