Dimethylformamide → 2-Chloro-3-[4-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-piperazinyl]pyrazine
Reaction equation
[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[CH:26]([N:27]([CH:28]([CH3:29])[CH3:30])[CH2:31][CH3:32])([CH3:33])[CH3:34].[Cl:18][c:19]1[n:20][cH:21][cH:22][n:23][c:24]1[Cl:25].[O:1]1[CH:2]([CH2:11][N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2>>[O:1]1[CH:2]([CH2:11][N:12]2[CH2:13][CH2:14][N:15]([c:24]3[c:19]([Cl:18])[n:20][cH:21][cH:22][n:23]3)[CH2:16][CH2:17]2)[CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2Participants
5
Sources & evidence
- ORD record
- ord-d6a15ffb52f146a09b11284c60cf7d26
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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