Methanol → C-(1-Benzyl-4-phenyl-piperazin-2-yl)-methylamine

HRID 958281Notes

Reaction equation

HRID 958281 reaction equation
[Al+3:24].[CH3:40][OH:41].[Cl:37][CH2:38][Cl:39].[H-:23].[H-:26].[H-:27].[H-:28].[Li+:25].[Na+:31].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH-:30].[OH2:29].[c:1]1([N:7]2[CH2:8][CH:9]([C:20](=[O:21])[NH2:22])[N:10]([CH2:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([N:7]2[CH2:8][CH:9]([CH2:20][NH2:22])[N:10]([CH2:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

11

Reactant 10

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 109900971-Benzyl-4-phenyl-piperazine-2-carboxamide

Product 1

HCID 11044210C-(1-Benzyl-4-phenyl-piperazin-2-yl)-methylamine

Sources & evidence

ORD record
ord-03e88ee33bb049eeb679140127631e50
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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