Methanol → N-(3-chloro-4-methoxyphenylmethyl)-4-[bis(4-trifluoromethoxyphenyl)hydroxymethyl]piperidine
Reaction equation
[BH3:45].[CH3:42][S:43][CH3:44].[CH3:46][OH:47].[Cl:1][c:2]1[cH:3][c:4]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([C:18]([OH:19])([c:20]3[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]3)[c:31]3[cH:32][cH:33][c:34]([O:37][C:38]([F:39])([F:40])[F:41])[cH:35][cH:36]3)[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]1[O:8][CH3:9].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:10][N:12]2[CH2:13][CH2:14][CH:15]([C:18]([OH:19])([c:20]3[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]3)[c:31]3[cH:32][cH:33][c:34]([O:37][C:38]([F:39])([F:40])[F:41])[cH:35][cH:36]3)[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]1[O:8][CH3:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7a3e02d57ddc4a45ae8ac8eaa708ec7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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