Dimethylformamide → 2-(4-Chloromethyl-5-methyl-pyridin-2-ylamino)-thiazole-5-carbonitrile
Reaction equation
[CH3:18][N:19]([CH3:20])[CH:21]=[O:22].[Cl:28][CH2:29][Cl:30].[OH:1][CH2:2][c:3]1[cH:4][c:5]([NH:10][c:11]2[s:12][c:13]([C:16]#[N:17])[cH:14][n:15]2)[n:6][cH:7][c:8]1[CH3:9].[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[CH2:2]([c:3]1[cH:4][c:5]([NH:10][c:11]2[s:12][c:13]([C:16]#[N:17])[cH:14][n:15]2)[n:6][cH:7][c:8]1[CH3:9])[Cl:25]Participants
5
Sources & evidence
- ORD record
- ord-eaafe740d3d4495c9d3b029227995748
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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