Tetrahydrofuran → 4-Morpholinobenzylamine

HRID 958962Notes

Reaction equation

HRID 958962 reaction equation
[Al+3:16].[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[H-:15].[H-:18].[H-:19].[H-:20].[Li+:17].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([C:11]#[N:12])[cH:13][cH:14]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([CH2:11][NH2:12])[cH:13][cH:14]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 3948084-Morpholinobenzonitrile

Product 1

HCID 27764584-Morpholinobenzylamine

Sources & evidence

ORD record
ord-1c56bd21fd7b44a995065850871184df
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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