Dimethylformamide → 3-(4-fluorophenyl)prop-2-enamide

HRID 959109Notes

Reaction equation

HRID 959109 reaction equation

[Cl:18][C:19]([C:20]([Cl:21])=[O:22])=[O:23].[Cl:24][CH2:25][Cl:26].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[CH:7][C:8](=[O:9])[OH:10])[cH:11][cH:12]1.[O:13]=[CH:14][N:15]([CH3:16])[CH3:17]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[CH:7][C:8](=[O:9])[NH2:15])[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 6228Dimethylformamide

HCID 6344Dichloromethane

HCID 65578Oxalyl chloride

HCID 980703-(4-Fluorophenyl)-2-propenoic acid

Product 1

HCID 9236013-(4-fluorophenyl)prop-2-enamide

Sources & evidence

ORD record: ord-32b585c84f834d97a361082aa0adf855
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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