Hydrochloric Acid → N-(2,6-Dichloro-5-quinolinyl)-cyclohexaneacetamide

HRID 959626Notes

Reaction equation

HRID 959626 reaction equation
[CH3:26][N:27]1[CH2:28][CH2:29][CH2:30][C:31]1=[O:32].[CH:14]1([CH2:20][C:21](=[O:22])[OH:23])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([Cl:13])[c:8]([NH2:12])[c:9]2[cH:10][cH:11]1.[ClH:25].[OH2:24]>>[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([Cl:13])[c:8]([NH:12][C:21]([CH2:20][CH:14]3[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]3)=[O:22])[c:9]2[cH:10][cH:11]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 21363Cyclohexaneacetic acidHCID 248203742,6-Dichloroquinolin-5-amine

Product 1

HCID 86012996N-(2,6-Dichloro-5-quinolinyl)-cyclohexaneacetamide

Sources & evidence

ORD record
ord-18d30d94b4984f659e3154ca75849067
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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