Chloride → N-Cyclopropyl-4-methyl-3-(1-oxo-1,2-dihydro-isoquinolin-6-yl)-benzamide

HRID 959658Notes

Reaction equation

HRID 959658 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:6][c:7]1[c:8](-[c:16]2[cH:17][c:18]3[cH:19][cH:20][nH:21][c:22](=[O:26])[c:23]3[cH:24][cH:25]2)[cH:9][c:10]([C:11](=[O:12])[OH:13])[cH:14][cH:15]1.[CH:27]1([NH2:30])[CH2:28][CH2:29]1.[CH:2]([Mg+:3])([CH3:4])[CH3:5].[Cl-:1]>>[CH3:6][c:7]1[c:8](-[c:16]2[cH:17][c:18]3[cH:19][cH:20][nH:21][c:22](=[O:26])[c:23]3[cH:24][cH:25]2)[cH:9][c:10]([C:11](=[O:12])[NH:30][CH:27]2[CH2:28][CH2:29]2)[cH:14][cH:15]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 69828CyclopropylamineHCID 67400847HCID 67400847, compoundHCID 178461726HCID 178461726, compound

Product 1

HCID 25020457N-Cyclopropyl-4-methyl-3-(1-oxo-1,2-dihydro-isoquinolin-6-yl)-benzamide

Sources & evidence

ORD record
ord-7a0557b8e6d24327a5e6fb68b9099eca
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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