Dimethyl Sulfoxide → Tert-butyl 3-oxopyrrolidine-1-carboxylate

HRID 959661Notes

Reaction equation

HRID 959661 reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH:20]([OH:23])[CH2:21][CH2:22]1.[CH2:31]([Cl:32])[Cl:33].[CH3:1][S:2]([CH3:3])=[O:4].[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[Cl:5][C:6]([C:7]([Cl:8])=[O:9])=[O:10].[OH2:34]>>[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][C:20](=[O:23])[CH2:21][CH2:22]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 44169391-Boc-3-pyrrolidinol

Product 1

HCID 471360Tert-butyl 3-oxopyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-5ac21417af8542b2b3c53024865781dc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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