Tetrahydrofuran → 5-Bromo-3,4-difluoro-2-((2-fluorophenyl)amino)benzoic acid

HRID 959951Notes

Reaction equation

[Br:19][c:20]1[c:21]([F:31])[c:22]([F:30])[c:23]([F:29])[c:24]([C:25](=[O:26])[OH:27])[cH:28]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:10][Si:11]([N-:12][Si:13]([CH3:14])([CH3:15])[CH3:16])([CH3:17])[CH3:18].[Li+:9].[NH2:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[F:8]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[F:8])[c:23]1[c:22]([F:30])[c:21]([F:31])[c:20]([Br:19])[cH:28][c:24]1[C:25](=[O:26])[OH:27]