Sodium ion → tert-Butyl 3-(tert-butoxycarbonylphenylmethyl)-5-cyano-2-oxo-2,3-dihydro-benzimidazole-1-carboxylate

HRID 960015Notes

Reaction equation

HRID 960015 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](=[O:19])[nH:10][c:11]2[c:12]1[cH:13][cH:14][c:15]([C:17]#[N:18])[cH:16]2.[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27]([CH:28]([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[Br:35])=[O:36].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[H-:21].[Na+:20].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[c:9](=[O:19])[n:10]([CH:28]([C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:36])[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:11]2[c:12]1[cH:13][cH:14][c:15]([C:17]#[N:18])[cH:16]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 166653HydrideHCID 11000147Tert-butyl 2-bromo-2-phenylacetateHCID 249009585-Cyano-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid tert-butyl ester

Product 1

HCID 66755109tert-Butyl 3-(tert-butoxycarbonylphenylmethyl)-5-cyano-2-oxo-2,3-dihydro-benzimidazole-1-carboxylate

Sources & evidence

ORD record
ord-50de48cc5c8148199c2529b4b8ab6d00
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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