Bicarbonate Ion → 5-phenyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine

HRID 960111Notes

Reaction equation

HRID 960111 reaction equation
[Br:10][c:11]1[cH:12][c:13]2[c:14]([n:15][cH:16]1)[n:17]([S:20](=[O:21])(=[O:22])[c:23]1[cH:24][cH:25][c:26]([CH3:29])[cH:27][cH:28]1)[cH:18][cH:19]2.[C:30](=[O:31])([OH:32])[O-:33].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[Na+:34].[c:1]1([B:7]([OH:8])[OH:9])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:11]2[cH:12][c:13]3[c:14]([n:15][cH:16]2)[n:17]([S:20](=[O:21])(=[O:22])[c:23]2[cH:24][cH:25][c:26]([CH3:29])[cH:27][cH:28]2)[cH:18][cH:19]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 66827Phenylboronic AcidHCID 224773531H-Pyrrolo[2,3-B]pyridine, 5-bromo-1-[(4-methylphenyl)sulfonyl]-

Product 1

HCID 224773445-phenyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-2a4d46a5612d4b37bca8bb84effb8871
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…