Isopropanol → (4-phenethyloxy-cyclohexyl)-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine

HRID 960214Notes

Reaction equation

HRID 960214 reaction equation
[CH3:36][CH:37]([OH:38])[CH3:39].[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[Cl:17][c:18]1[c:19]2[c:20]([n:21][cH:22][n:23]1)[nH:24][n:25][cH:26]2.[c:1]1([CH2:7][CH2:8][O:9][CH:10]2[CH2:11][CH2:12][CH:13]([NH2:16])[CH2:14][CH2:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH2:8][O:9][CH:10]2[CH2:11][CH2:12][CH:13]([NH:16][c:18]3[c:19]4[c:20]([n:21][cH:22][n:23]3)[nH:24][n:25][cH:26]4)[CH2:14][CH2:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 3776IsopropanolHCID 81531DiisopropylethylamineHCID 2210954-Chloro-1H-pyrazolo[3,4-d]pyrimidineHCID 59834923trans-4-(2-Phenyl-ethoxy)-cyclohexylamine

Product 1

HCID 11551785(4-phenethyloxy-cyclohexyl)-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine

Sources & evidence

ORD record
ord-e90e3c256ee347458fb8b283d9e87123
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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