Hydrochloric Acid → 5-(4-Hydroxy-1-methyl-piperidin-4-ylmethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one

HRID 960285Notes

Reaction equation

HRID 960285 reaction equation
[CH2:1]([O:3][C:4](=[O:2])[c:6]1[c:7]([CH2:12][CH2:13][NH:14][CH2:15][C:16]2([OH:23])[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]2)[nH:8][cH:9][c:10]1[CH3:11])[CH3:5].[ClH:27].[Li+:26].[OH-:25].[OH2:24].[OH2:28]>>[O:3]=[C:4]1[c:6]2[c:7]([nH:8][cH:9][c:10]2[CH3:11])[CH2:12][CH2:13][N:14]1[CH2:15][C:16]1([OH:23])[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 961HydroxideHCID 962Water2×HCID 28486Lithium ionHCID 666078142-{2-[(4-hydroxy-1-methyl-piperidin-4-ylmethyl)-amino]-ethyl}-4-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

Product 1

HCID 666066255-(4-Hydroxy-1-methyl-piperidin-4-ylmethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one

Sources & evidence

ORD record
ord-4c1731f2a3d64162a4b7ef8ba6db2e21
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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