Tetrahydrofuran → 3-Ethoxy-5-(2,2,2-trifluoroethoxy)benzaldehyde

HRID 960513Notes

Reaction equation

HRID 960513 reaction equation
[Al+3:21].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([O:16][CH2:17][CH3:18])[cH:7][c:8]([O:10][CH2:11][C:12]([F:13])([F:14])[F:15])[cH:9]1)=[O:19].[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22].[O:31]=[Mn:32]=[O:33]>>[O:2]=[CH:3][c:4]1[cH:5][c:6]([O:16][CH2:17][CH3:18])[cH:7][c:8]([O:10][CH2:11][C:12]([F:13])([F:14])[F:15])[cH:9]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 14801Manganese dioxideHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 68699922HCID 68699922, compound

Product 1

HCID 587063453-Ethoxy-5-(2,2,2-trifluoroethoxy)benzaldehyde

Sources & evidence

ORD record
ord-9603d13f60914c0bbac5b845bf6aea60
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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