Sodium ion → Ethyl 1-benzoylpiperidine-4-carboxylate

HRID 960933Notes

Reaction equation

HRID 960933 reaction equation
[C:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)(=[O:26])[Cl:27].[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[NH:1]1[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[CH2:10][CH2:11]1.[Na+:12].[Na+:13].[O-:14][C:15](=[O:16])[O-:17].[OH2:18]>>[N:1]1([C:19]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)=[O:26])[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[CH2:10][CH2:11]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 7412Benzoyl chlorideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 735824Ethyl 1-benzoylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-732a1b685eb741079a16fc63ea10ae91
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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