Tetrahydrofuran → 4-(Pyridin-2-ylmethyl)-1,4-diaza-bicyclo[3.2.2]nonane

HRID 961223Notes

Reaction equation

HRID 961223 reaction equation
[Al+3:2].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[N:7]12[CH2:8][CH2:9][N:10]([C:16](=[O:17])[c:18]3[n:19][cH:20][cH:21][cH:22][cH:23]3)[CH:11]([CH2:12][CH2:13]1)[CH2:14][CH2:15]2>>[N:7]12[CH2:8][CH2:9][N:10]([CH2:16][c:18]3[n:19][cH:20][cH:21][cH:22][cH:23]3)[CH:11]([CH2:12][CH2:13]1)[CH2:14][CH2:15]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 68865039(1,4-Diazabicyclo[3.2.2]non-4-yl)(pyridin-2-yl)methanone

Product 1

HCID 114359054-(Pyridin-2-ylmethyl)-1,4-diaza-bicyclo[3.2.2]nonane

Sources & evidence

ORD record
ord-8f0b4d8c73964a75ae4b1c68036c0db3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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