Hydrochloric Acid → 5-(Aminomethyl)-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine
Reaction equation
[BH3:22].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:30][OH:31].[ClH:23].[NH2:1][c:2]1[n:3][cH:4][c:5]([C:6]#[N:7])[cH:8][c:9]1[O:10][CH:11]([CH3:12])[c:13]1[c:14]([Cl:21])[c:15]([F:20])[cH:16][cH:17][c:18]1[Cl:19].[OH2:24]>>[NH2:1][c:2]1[n:3][cH:4][c:5]([CH2:6][NH2:7])[cH:8][c:9]1[O:10][CH:11]([CH3:12])[c:13]1[c:14]([Cl:21])[c:15]([F:20])[cH:16][cH:17][c:18]1[Cl:19]Participants
7
Sources & evidence
- ORD record
- ord-89d6bb78a0b24dce8267af35517f15d2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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