Dimethylformamide → 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione

HRID 961383Notes

Reaction equation

HRID 961383 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[Cl:1][c:2]1[c:3]([C:4]([CH2:5][Cl:6])=[O:7])[cH:8][cH:9][c:10]([Cl:12])[cH:11]1.[Cs+:28].[Cs+:29].[O:13]=[C:14]1[NH:15][C:16](=[O:17])[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]21.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[Cl:1][c:2]1[c:3]([C:4]([CH2:5][N:15]2[C:14](=[O:13])[c:23]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[C:16]2=[O:17])=[O:7])[cH:8][cH:9][c:10]([Cl:12])[cH:11]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6809PhthalimideHCID 19660Carbonate IonHCID 202502,2',4'-TrichloroacetophenoneHCID 104967Cesium cation2×

Product 1

HCID 7367782-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-9f9f3f5019f14da19f4f9d4604c89076
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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