HRID961427

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID81531

Diisopropylethylamine

C8H19N

结构：COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1N

HCID57416157

tert-Butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate

C17H26N2O3

结构：CC(C)(C)NS(=O)(=O)c1cccc(-c2ccc3cnc(O)nn23)c1

HCID178449976

未命名化合物

PRODUCTS

生成物

结构：COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2ccc(-c3cccc(S(=O)(=O)NC(C)(C)C)c3)n2n1

HCID66712008

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b2ef75f2327e46598ca509ade4db7dee
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[cH:19][n:20][c:21]([OH:24])[n:22][n:23]23)[cH:12][cH:13][cH:14]1.[C:34]([CH3:35])([CH3:36])([CH3:37])[O:38][C:39](=[O:40])[N:41]1[CH2:42][CH2:43][CH:44]([c:47]2[cH:48][c:49]([O:54][CH3:55])[c:50]([NH2:53])[cH:51][cH:52]2)[CH2:45][CH2:46]1.[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[O:56]=[CH:57][N:58]([CH3:59])[CH3:60]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[cH:19][n:20][c:21]([NH:53][c:50]4[c:49]([O:54][CH3:55])[cH:48][c:47]([CH:44]5[CH2:43][CH2:42][N:41]([C:39]([O:38][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:40])[CH2:46][CH2:45]5)[cH:52][cH:51]4)[n:22][n:23]23)[cH:12][cH:13][cH:14]1