Hydrochloric Acid → 4-(7-Amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindol-4-yl)-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]3[c:19]([c:20]([N+:23]([O-:24])=[O:25])[cH:21][cH:22]2)[C:18](=[O:26])[N:17]([CH3:27])[CH2:16]3)[CH2:12][CH2:13]1.[CH3:31][CH2:32][OH:33].[ClH:28].[Fe:34].[Na+:30].[OH-:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]3[c:19]([c:20]([NH2:23])[cH:21][cH:22]2)[C:18](=[O:26])[N:17]([CH3:27])[CH2:16]3)[CH2:12][CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fa0bc6e3a12e41d185faa2f8dbfcde41
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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