Sodium ion → (1-Methyl-3-piperidyl)methanol

HRID 961893Notes

Reaction equation

HRID 961893 reaction equation
[Al+3:2].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[Na+:23].[OH-:22].[OH2:24].[OH:7][CH2:8][CH:9]1[CH2:10][N:11]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:12][CH2:13][CH2:14]1>>[OH:7][CH2:8][CH:9]1[CH2:10][N:11]([CH3:15])[CH2:12][CH2:13][CH2:14]1

Participants

9

Reactant 8

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 2763851tert-Butyl 3-(hydroxymethyl)piperidine-1-carboxylate

Product 1

HCID 97998(1-Methyl-3-piperidyl)methanol

Sources & evidence

ORD record
ord-514ef5cf1cbe477d959b0ec2cb5eb5a9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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