Acetate → Tert-butyl 3-[4-[(4-hydroxyphenyl)-(oxan-4-ylidene)methyl]phenyl]prop-2-enoate

HRID 962013Notes

Reaction equation

HRID 962013 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]([c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)=[C:16]2[CH2:17][CH2:18][O:19][CH2:20][CH2:21]2)[cH:6][cH:7]1.[C:22]([CH:23]=[CH2:24])(=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[O-:45][C:46]([CH3:47])=[O:48].[O-:49][C:50]([CH3:51])=[O:52].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[OH2:38].[Pd+2:44]>>[c:2]1([CH:24]=[CH:23][C:22](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[cH:3][cH:4][c:5]([C:8]([c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)=[C:16]2[CH2:17][CH2:18][O:19][CH2:20][CH2:21]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 15458tert-Butyl acrylateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 686541974-[(4-Bromophenyl)(tetrahydro-4H-pyran-4-ylidene)methyl]phenol

Product 1

HCID 90796704Tert-butyl 3-[4-[(4-hydroxyphenyl)-(oxan-4-ylidene)methyl]phenyl]prop-2-enoate

Sources & evidence

ORD record
ord-ecb13bc79f5142468efcb5df7da0e1ce
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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