Sodium ion → 8-[(4-Bromophenyl)methyl]4-hydroxymethyl-2-methyl-5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one

HRID 962107Notes

Reaction equation

HRID 962107 reaction equation
[BH4-:23].[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]2[C:10](=[O:22])[CH2:11][CH2:12][c:13]3[c:14]2[n:15][c:16]([CH3:21])[n:17][c:18]3[CH:19]=[O:20])[cH:6][cH:7]1.[CH:30]([OH:31])([CH3:32])[CH3:33].[Na+:24].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]2[C:10](=[O:22])[CH2:11][CH2:12][c:13]3[c:14]2[n:15][c:16]([CH3:21])[n:17][c:18]3[CH2:19][OH:20])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 3776IsopropanolHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 104285708-[(4-Bromophenyl)methyl]-2-methyl-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-4-carbaldehyde

Product 1

HCID 104737918-[(4-Bromophenyl)methyl]4-hydroxymethyl-2-methyl-5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one

Sources & evidence

ORD record
ord-a1ba9cb676c44bca833c4c8fb5896279
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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