Chloride → 3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)-1-methylcyclobutanol
Reaction equation
[Br:1][c:2]1[n:3][c:4]([CH:12]2[CH2:13][C:14](=[O:16])[CH2:15]2)[n:5]2[c:6]1[c:7]([Cl:11])[n:8][cH:9][cH:10]2.[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:18][Mg+:19].[Cl-:17]>>[Br:1][c:2]1[n:3][c:4]([CH:12]2[CH2:13][C:14]([OH:16])([CH3:18])[CH2:15]2)[n:5]2[c:6]1[c:7]([Cl:11])[n:8][cH:9][cH:10]2Participants
5
Sources & evidence
- ORD record
- ord-44ceca13542c4836adcb9756c0d8a239
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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