Hydrochloric Acid → (5-(4-Bromophenyl)isoxazol-4-yl)methanol

HRID 962142Notes

Reaction equation

HRID 962142 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:10][n:11][o:12]2)[cH:6][cH:7]1.[CH2:19]([Al+:20][CH2:21][CH:22]([CH3:23])[CH3:24])[CH:25]([CH3:26])[CH3:27].[ClH:28].[H-:18].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:13][OH:14])[cH:10][n:11][o:12]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 166653HydrideHCID 16686348Bis(2-methylpropyl)alumanyliumHCID 22220993Ethyl 5-(4-bromophenyl)isoxazole-4-carboxylate

Product 1

HCID 22221249(5-(4-Bromophenyl)isoxazol-4-yl)methanol

Sources & evidence

ORD record
ord-277af3a15eac4756ba23a0fa8e4c1422
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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