Hydrochloric Acid → 2,4-Diamino-5-methylquinazoline-6-carbonitrile

HRID 962267Notes

Reaction equation

HRID 962267 reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[ClH:15].[Cu+2:52].[K+:40].[K+:41].[K:20][C:21]#[N:22].[N:16]([O-:17])=[O:18].[NH2:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([NH2:14])[c:8]([CH3:13])[c:9]2[c:10]([NH2:12])[n:11]1.[Na+:19].[OH2:35].[OH2:42].[OH2:43].[OH2:44].[OH2:45].[OH2:46].[S:47]([O-:48])([O-:49])(=[O:50])=[O:51].[n:23]1[c:24]2[c:25]([cH:26][cH:27][cH:28][cH:29]2)[cH:30][n:31][c:32]1[N+:33]#[N:34]>>[NH2:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([C:21]#[N:22])[c:8]([CH3:13])[c:9]2[c:10]([NH2:12])[n:11]1

Participants

12

Reactant 11

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 923Sodium ionHCID 946NitriteHCID 962Water6×HCID 1117Sulfate IonHCID 19660Carbonate IonHCID 27099Cupric cationHCID 134137782,4,6-Triamino-5-methylquinazolineHCID 86749621Quinazoline diazoniumHCID 178511842HCID 178511842, compound

Product 1

HCID 138854082,4-Diamino-5-methylquinazoline-6-carbonitrile

Sources & evidence

ORD record
ord-e3fae3f132a44422ae2433810ab2fedc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…