→ Ethyl 1,2,3,4-tetrahydro-4,6-dimethyl-2-oxo-5-pyrimidinecarboxylate

HRID 962319Notes

Reaction equation

HRID 962319 reaction equation
CC=O.CCO.CCOC(=O)CC(C)=O.NC(N)=O.O.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>CCOC(=O)C1=C(C)NC(=O)NC1C

Participants

6

Reactant 0

No Reactant data yet.

Product 1

HCID 603058Ethyl 1,2,3,4-tetrahydro-4,6-dimethyl-2-oxo-5-pyrimidinecarboxylateYield 67%

Reagents, catalysts & solvents 5

HCID 177AcetaldehydeOtherHCID 702EthanolOther2×HCID 1176UreaOtherHCID 8868Ethyl AcetoacetateOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-38f398cd1ab24e14b7adcbf3f83c131d
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Reaction notes

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