→ 5-Acetyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one

HRID 962332Notes

Reaction equation

HRID 962332 reaction equation
CC(=O)CC(C)=O.CCO.NC(N)=O.O.O=Cc1ccccc1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>CC(=O)C1=C(C)NC(=O)NC1c1ccccc1

Participants

6

Reactant 0

No Reactant data yet.

Product 1

HCID 5926405-Acetyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-oneYield 53%

Reagents, catalysts & solvents 5

HCID 240BenzaldehydeOtherHCID 702EthanolOther2×HCID 1176UreaOtherHCID 31261AcetylacetoneOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-24f42e54a6ed488e811e971e8eb5e0c0
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Reaction notes

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