反应详情

A mixture of 4-chlorophenol (100 g), 1-bromo-2-chloroethane (335 g), potassium carbonate (129 g) and acetone (2 l) was boiled under reflux with stirring for 18 hours. The mixture was evaporated to dryness under reduced pressure and then dichloromethane was added to the cool residue. The mixture was filtered and the filtrate washed with 5M sodium hydroxide solution, water, dried, filtered and evaporated to give 2-chloroethyl 4-chlorophenyl ether as an oil.

1. temperatureunder reflux
2. customThe mixture was evaporated to dryness under reduced pressure
3. additiondichloromethane was added to the cool residue
4. filtrationThe mixture was filtered
5. washthe filtrate washed with 5M sodium hydroxide solution, water
6. customdried
7. filtrationfiltered
8. customevaporated