HRID962697

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID76257

Diethylphosphorocyanidate

C5H10NO3P

结构：CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

HCID475445

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(C#N)CC[C@]4(C)[C@H]3CC[C@]12C

HCID67646951

N-tert-Butyl-3-cyanoandrosta-3,5-diene-17beta-carboxamide

C25H36N2O

PROCEDURE

实验过程

Following a procedure similar to that described in Example 2(c), but using 100 mg of N-t-butyl-3-oxo-4-androstene-17β-carboxamide (prepared as described in Preparation 1), 0.2 ml of diethyl cyanophosphate and 200 mg of a boron trifluoride-diethyl ether complex, 86 mg of the title compound were obtained as a crystalline substance, melting at 198° to 200° C.