Diisopropylamine → {1-benzenesulfonyl-2-[1-hydroxy-2-(tetrahydro-pyran-4-yl)-ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][c:10]2[c:11]([n:12][cH:13]1)[n:14]([S:17](=[O:18])(=[O:19])[c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[cH:15][cH:16]2)=[O:26].[CH2:35]([Li:36])[CH2:37][CH2:38][CH3:39].[CH3:40][CH2:41][CH2:42][CH2:43][CH2:44][CH3:45].[CH:27]([N-:28][CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[CH:46]([NH:47][CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[Li+:34].[O:53]1[CH2:54][CH2:55][CH:56]([CH2:59][CH:60]=[O:61])[CH2:57][CH2:58]1.[O:62]1[CH2:63][CH2:64][CH2:65][CH2:66]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][c:10]2[c:11]([n:12][cH:13]1)[n:14]([S:17](=[O:18])(=[O:19])[c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[c:15]([CH:60]([CH2:59][CH:56]1[CH2:55][CH2:54][O:53][CH2:58][CH2:57]1)[OH:61])[cH:16]2)=[O:26]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-bffeb487230641168c778c521397f146
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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