Hydrochloric Acid → HCID 19079193, compound

HRID 964104Notes

Reaction equation

HRID 964104 reaction equation
[NH2:1][C:2]1[C:7]([CH2:8][CH2:9][N:10]2[C:14](=[O:15])[C:13]3=[CH:16][CH:17]=[CH:18][CH:19]=[C:12]3[C:11]2=[O:20])=[CH:6][CH:5]=[CH:4][N:3]=1.[ClH:21]>CO>[ClH:21].[NH2:1][C:2]1[C:7]([CH2:8][CH2:9][N:10]2[C:11](=[O:20])[C:12]3=[CH:19][CH:18]=[CH:17][CH:16]=[C:13]3[C:14]2=[O:15])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 152314972-Amino-3-(2-(phthalimido)ethyl]pyridine

Product 1

HCID 19079193HCID 19079193, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

In 5 ml of methanol was dissolved 237 mg (0.792 mmol) of 2-amino-3-(2-(phthalimido)ethyl]pyridine. The solution was treated with 5 ml (10 mmol) of a 2N solution of hydrogen chloride in methanol. The solvent was distilled off to obtain the desired powder. The powder thus obtained was washed with ether to obtain 233 mg of the desired compound (yield: 79.0%, pale yellow powder).

Workup

  1. distillationThe solvent was distilled off
  2. customto obtain the desired powder
  3. customThe powder thus obtained
  4. washwas washed with ether

Sources & evidence

ORD record
ord-3a7bc5ade47a4b01abaff350d707a98c
Source dataset
uspto-grants-1998_06
Patent number
US05767121

Reaction notes

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