Dichloromethane → 4-Chloro-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazoline
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([O:14][CH:15]2[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]2)[c:6]2[c:7](=[O:13])[nH:8][cH:9][n:10][c:11]2[cH:12]1.[CH:22]([N:23]([CH:24]([CH3:25])[CH3:26])[CH2:27][CH3:28])([CH3:29])[CH3:30].[Cl:36][CH2:37][Cl:38].[P:31]([Cl:32])([Cl:33])([Cl:34])=[O:35]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([O:14][CH:15]2[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]2)[c:6]2[c:7]([Cl:33])[n:8][cH:9][n:10][c:11]2[cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-ca1bd22e0b724606afea0cda242f9b11
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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