huagongshe.com
HRID967223

反应详情

EQUATION

反应方程式

HRID 967223 的结构方程式

REACTANTS

反应物

3
结构：c1c[nH]cn1
HCID795

Imidazole

C3H4N2

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CN(C[C@H]1CC[C@H](COS(C)(=O)=O)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1
HCID178484090

未命名化合物

PRODUCTS

生成物

1
结构：CN(C[C@H]1CC[C@H](Cn2ccnc2)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1
HCID178484039

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

In analogy to the procedure described in example 25.1, trans-methanesulfonic acid 4-{[methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-methyl}-cyclohexylmethyl ester (example 5.2) was reacted with imidazole in N,N-dimethylformamide in the presence of sodium hydride to yield trans-N-(4-imidazol-1-ylmethyl-cyclohexylmethyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide as colorless solid, MS: 416 (MH+).