Hydrazine hydrate (1:1) → (3-Fluoro-2-nitro-phenyl)-hydrazine

HRID 968299Notes

Reaction equation

HRID 968299 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](F)[C:3]=1[N+:9]([O-:11])=[O:10].O.[NH2:13][NH2:14]>C1COCC1>[F:1][C:2]1[C:3]([N+:9]([O-:11])=[O:10])=[C:4]([NH:13][NH2:14])[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 879221,3-Difluoro-2-nitrobenzene

Product 1

HCID 22139869(3-Fluoro-2-nitro-phenyl)-hydrazine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 0.01 M 2,6-difluoronitrobenzene and 0.01 M hydrazine hydrate (99% strength) in 30 ml of THF was stirred overnight at RT (exothermic reaction) and the residue was brought to crystallization after distilling off the solvent by treating with diisopropyl ether. Crystalline substance, m.p.: 93-95° C.

Workup

  1. custom(exothermic reaction)
  2. customthe residue was brought to crystallization
  3. distillationafter distilling off the solvent
  4. additionby treating with diisopropyl ether

Sources & evidence

ORD record
ord-f7f3ff53a6224db4934b374953e7b54d
Source dataset
uspto-grants-2005_10
Patent number
US06958357B2

Reaction notes

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